OREGON STATE UNIVERSITY
Open search box
| Title | Effects of α-lipoic and ascorbic acid on the muscle and brain fatty acids and antioxidant profile of the South American pacu Piaractus mesopotamicus |
| Publication Type | Journal Article |
| Year of Publication | 2007 |
| Authors | Trattner, S, Pickova, J, Park, KH, Rinchard, J, Dabrowski, K |
| Journal | Aquaculture |
| Volume | 273 |
| Issue | 1 |
| Pagination | 158 - 164 |
| Date Published | 2007 |
| ISBN Number | 00448486 (ISSN) |
| Keywords | Fatty acid, Lipoic acid, Teleost, Vitamin C, Vitamin E |
| Abstract | The effects of dietary α-lipoic acid (LA) and vitamin C on the fatty acid (FA) composition in the brain and muscle and vitamins E and C levels in the brain were studied in the fish Piaractus mesopotamicus. A two-factorial design, where diets were devoid or supplemented with ascorbate (500 mg AA kg−1) and/or lipoic acid (1000 mg kg−1), was used. The levels of eicosapentaenoic acid (20:5 n−3, EPA) increased ( P < 0.01) in muscle polar lipids (PL) in LA groups (6.93% ± 0.43 vs. 5.83% ± 0.40 and 6.68% ± 0.53 vs. 6.00% ± 0.39), and the same trend was also seen in the brain, however not significant. These changes are suggested to be caused by a change in lipid metabolism rather than being a direct effect of protection by LA against lipid peroxidation. No interaction of vitamin C and LA neither effects of LA on vitamin E (15.1–19.2 mg α-tocopherol g−1 tissue) or vitamin C (total AA, 41.7–89.8 μg g−1 tissue) in brain was detected. |
| URL | http://www.sciencedirect.com/science/article/pii/S0044848607009271 |
| Notice of Publication Number | NOP 07-225 (English) |
